retinoicacid相关论文
Male meiosis is a complex process whereby spermatocytes undergo cell division to form haploid cells.This review focuses ......
Expression of the retinoic acid-metabolizing enzymes RALDH2 and CYP26b1 during mouse postnatal testi
Aim: To study the expression pattern of the retinoic acid metabolizing enzymes RALDH2 and CYP26bl during mouse postnatal......
Generation of male germ cells from induced pluripotent stem cells (iPS cells): an in vitro and in vi
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Retinoic acid (RA) has been shown to induce congenital clubfoot in animal models, but it is unknown whether the effect o......
Five and fewer digits are autopod patterns seen in modern tetrapods, indicating highly conserved regulatory programs in ......
Foxc1a works upstream of Fgf and Notch signaling to control zebrafish somitogenesis by restricting R
Foxc1a is a member of forkhead transcription factors.It plays essential roles in vertebrate somitogenesis.However,little......
Association between Circulating Retinoic Acid and Metabolic Syndrome in Chinese People--Retinoic Aci
Retinoic acid (RA) was demonstrated to exert protective effect on obesity and the metabolic syndrome in animal studies.T......
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Epigenetic modification controls the response of insm1b to RA signaling in zebrafish early developme
Retinoic acid(RA)signaling plays crucial roles in early embryonic development of vertebrates through the ligand,RA,b......
[Objective] To screen the genes related to cleft palate induced by Retinoic acid (RA), laying foundation for the res......
视黄酸(RA)处理SMMC-7721人肝癌细胞株72小时后,胞浆、膜性组分的蛋白激酶C(PK-C)的活力及比活力均下降,活力分别下降44.9%和48.8%,......
Synergistic effects of brain-derived neurotrophic factor and retinoic acid on inducing the different
BACKGROUND; Under induction of retinoic acid (RA), bone marrow stromal cells (BMSCs) can differentiate into nerve cells ......
To date, little information has been available regarding genes involved in the regulation of embryonic cell development,......
Two potentially specific but relevant patterns of proteomic change Response of SH-SY5Y cells to diff
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Optimal time point for the transplantation of neural stem cells induced to differentiate with retino
Previous studies have demonstrated that differentiated neural stem cells (NSCs) are more suitable for transplantation th......
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In the field of developmental neurobiology, accurate and ordered regulation of the cell cycle and apoptosis are crucial ......
Retinoid X receptor α downregulation is required for tail and caudal spinal cord regeneration in the
Some adult vertebrate species,such as newts,axolotls and zebrafish,have the ability to regenerate their central nervous ......
Stra8基因的表达具有发育阶段性,且仅表达于减数分裂前的生殖细胞,它在生殖细胞的胞质和胞核中进行穿梭。视黄酸是维生素A的一种代谢......
目的:探讨维甲酸联合亚砷酸治疗初治急性早幼粒细胞白血病的临床疗效。方法回顾性的分析我院2012年1月~2015年8月初治的急性早幼粒......
近视是一种常见的导致视力障碍的眼科疾病,其患病率逐年升高,而目前临床上尚无有效的根治手段,原因在于近视的发病机制尚不明确.目......
Preparation of Mouse Embryonic Stem Cells and Cardiomyocyte Differentiation Induced with Retinoic Ac
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目的:从细胞水平对维A酸致小鼠腭裂畸形作用和叶酸是否有拮抗维A酸的致畸作用及其机制进行研究.方法:给予孕鼠过量维A酸,诱导胚胎......
目的 探讨维生素A酸(retinoic acid,RA)对大鼠缺血性脑损伤的保护作用及机制.方法 将54只SD大鼠分为假手术组、缺血对照组和RA治疗......
目的探讨维甲酸改善氟他胺诱导隐睾大鼠生精功能的相关机制,为临床预防隐睾患儿发生不育提供动物实验基础。方法30只雌性SD大鼠合笼......
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Downregulation of retinoic acid receptor-β2expression is linked to aberrant methylation in esophagea
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目的 探究维甲酸(RA)对乳鼠真皮成纤维细胞(DFB)及脂肪源干细胞(ADSCs)成骨诱导分化的影响.方法 分别离体培养5~7 d龄乳鼠DFB及ADSC......
Retinoic Aacid Diminished the Expression of MMP-2 in Hyperoxia-exposed Premature Rat Lung Fibroblast
This study examined the effects of retinoic acid (RA),PD98059,SP600125 and SB203580 on the hyperoxia-induced expression ......
目的 探讨Dishevelled2和Vangl2蛋白在过量维甲酸致昆明小鼠腭裂发生中的作用.方法采用免疫组织化学及图像分析方法,检测维甲酸致......
目的 观察维甲酸诱导小鼠胚胎神经管畸形中β-catenin表达水平变化.方法 孕鼠随机分为对照组和实验组.胚胎7.75 d时,实验组1次性胃......
目的 探讨桉叶油联合维甲酸(RA)对SD胎鼠脑组织转录因子Pax3、缝隙连接蛋白43(Cx43)表达的影响.方法SD孕鼠42只,随机分为6组,每组7......
BACKGROUND: Neural tube defects can be induced by abnormal factors in vivo or in vitro during development. However, the ......
目的 探讨Hoxd-13基因表达与大鼠肛门直肠畸形形成之间的相关性.方法 维甲酸制作大鼠肛门直肠畸形动物模型,分别于妊娠第12、13、1......
目的 观察维A酸受体β(RAR-β)在食管鳞癌中的表达及其与化疗疗效的关系.方法 52例中晚期食管鳞癌患者给予以顺铂(DDP)+5-氟尿嘧啶......
EFFECTS OF RETINOIC ACID ON PROLIFERATION AND DIFFERENTIATION OF A HUMAN OVARIAN CARCINOMA CELL LINE
Objective To observe the effects ofretinoic acid (RA) on the proliferation and differentiation of a human ovarian carcin......
从细胞周期调控这一途径探讨视黄酸抑制细胞增殖、诱导细胞分化的分子机制。结果显示:5×10^-6mol/L全反式视黄酸(ATRA)及劳维甲(AE)处理的HL-60细胞生长受......
探讨细胞周期素依赖性激酶在视黄酸对急性早幼粒细胞白血病HL-60细胞的增殖抑制和分化调控过程中的作用。方法应用真核细胞基因转染技术......
维甲酸是促分化的生物活性分子;Forskolin则系天然植物中的腺苷酸环化酶特异激活剂,能促进细胞内cAMP的积累而有抑制增殖作用。实验发现,维甲酸与Forskolin均......
目的观察转移因子胶囊联合消疣汤治疗扁平疣的疗效.方法将60例扁平疣患者随机分为治疗组34例和对照组26例.治疗组口服转移因子胶囊......
目的:研究全反式维甲酸(ATRA)治疗急性早幼粒细胞白血病(APL)常见及少见毒副反应。方法:回顾分析38例APL在ATRA治疗期间出现的毒副反应。......
目的:探讨维甲酸在预防和治疗肿瘤中的作用机制,分离受维甲酸调控的靶基因。方法:采用AP-PCR测序、Northern杂交及序列2同源分析等方法。结果:首次发现......
目的 探讨维生素A促进免疫细胞功能的机制。方法 采用逆转录--聚链反应,检测分析视黄酸(RA)对体外培养的脐血淋巴细胞(CBI)胰岛素生长因子1(IGF-1)及两......
目的观察全反式维甲酸(ATRA)对急性前髓性白血病细胞HL60生长的影响,探讨其抑制肿瘤生长的作用方式。方法建立急性前髓性白血病细胞H......